Understanding the Symptoms of Diabetic Peripheral Neuropathy
- Kevin Lowe M.D.
- Aug 17
- 2 min read

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes, affecting up to half of people living with the condition over time. It occurs when persistently high blood sugar damages the nerves—especially those farthest from the spinal cord, such as those in the feet and hands. Recognizing the symptoms early is vital, because timely intervention can help prevent progression, reduce discomfort, and protect overall quality of life.
Early Symptoms: Subtle but Important
In the early stages, symptoms of DPN may be mild and easy to overlook. People often describe:
Numbness or reduced ability to feel pain or temperature in the toes and feet
Tingling or “pins and needles” sensations that may come and go
Mild burning or prickling feelings, especially at night
Because these changes start gradually, they may not prompt concern right away. However, ignoring them increases the risk of developing more severe nerve damage.
Progression of Symptoms
As diabetic neuropathy advances, symptoms tend to become more noticeable and disruptive:
Sharp, stabbing, or burning pain in the feet and legs
Increased sensitivity to touch, where even light pressure from socks or bedsheets can feel painful (a phenomenon called allodynia)
Muscle weakness in the feet or hands
Loss of balance and coordination, especially when walking in the dark or on uneven ground
These symptoms often follow a “stocking-glove” distribution, meaning they start in the toes and feet, later involving the hands as the condition progresses.
Autonomic Involvement
Although DPN primarily affects the sensory nerves, it can also involve autonomic nerves, which control involuntary body functions. When this happens, symptoms may include:
Dizziness or fainting when standing up quickly (orthostatic hypotension)
Digestive issues such as constipation, diarrhea, or delayed stomach emptying (gastroparesis)
Abnormal sweating—either too much or too little
Urinary difficulties or erectile dysfunction
These symptoms can significantly impact quality of life but may be overlooked unless specifically discussed with a healthcare provider.
Why Recognizing Symptoms Matters
Identifying the symptoms of diabetic peripheral neuropathy early allows for:
Timely medical evaluation to rule out other causes of neuropathy
Better diabetes management to slow progression
Preventive foot care, which lowers the risk of ulcers, infections, and amputations
Symptom relief through medications, physical therapy, and lifestyle adjustments
When to Seek Medical Help
If you live with diabetes and notice numbness, tingling, burning pain, or unusual sensitivity in your feet or hands, it is important to discuss these symptoms with your healthcare provider. Early recognition and intervention can make a significant difference in outcomes.
Key Takeaway
Diabetic peripheral neuropathy develops gradually, starting with subtle sensations in the feet and potentially leading to pain, weakness, and balance issues. Recognizing and addressing these symptoms promptly is one of the most effective ways to maintain independence and protect long-term health.
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