High Creatinine on Your Blood Test? 5 Surprising Causes (Not Kidney Failure)
- Kevin Lowe M.D.
- Apr 4
- 1 min read
If your creatinine blood test came back high, you may be wondering what it means and whether it signals a kidney problem. In this video, we explain the most common causes of high creatinine levels and why an elevated result does not always mean kidney disease. Creatinine is a waste product produced by your muscles and filtered by the kidneys, but several non-kidney factors can cause it to rise.
You’ll learn:
• What a creatinine blood test measures
• Why creatinine levels can be high without kidney disease
• How muscle mass, exercise, and diet affect creatinine
• The effect of creatine supplements on blood creatinine
• How certain medications can raise creatinine levels
• How lab interference can sometimes cause false elevations
If you recently received blood work showing high creatinine, this video will help you understand what may be causing it and when you should follow up with your doctor.



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